Warning Label for Valdecoxib


The FDA said that it would require a new warning label for valdecoxib (Bex-tra®, Pfizer), another COX-2 inhibitor, because of potential heart problems associated with its use in people who had recently had heart bypass surgery.
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Results from a study of more than 1,500 patients who had just had cardiac surgery show that patients treated with valdecoxib for pain were more likely to have heart attacks, strokes, and blood clots in the legs and the lungs, than patients who did not receive this agent.