The “Polypill” for Heart Disease and Stroke

single pill might be able to reduce heart attacks and strokes by more than 80%, concludes a study from England. Heart attacks, stroke, and other pre­ventable cardiovascular diseases kill or seriously affect 50% of people in Britain.

Professor Nicholas Wald and Malcolm Law propose a “polypill” that would contain six active components—aspirin, a cholesterol-lowering drug, three blood pressure-lowering drugs at half the standard dose, and folic acid. The pill would be taken daily by all people aged 55 and over and is expected to have a huge effect on preventing disease in the Western world.
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Their radical strategy is based on evidence from more than 750 trials involving 400,000 participants.

These medications are well tolerated, and new problems are unlikely because they have been studied extensively and have often been used in combination.