The FDA has approved a five-day, once-daily IV and oral 750-mg regimen of generic levofloxacin (Levaquin drags, Ortho-McNeil, PriCara) for patients with complicated urinary tract infections (UTIs) and acute pyelonephritis (kidney infection).
Antibiotic resistance is making it more difficult to treat common urinary tract infections (UTIs). Resistance to betalactam antibiotics prompted a switch to trimethoprim drug/sulfamethoxazole (TMP/ SMX, Bactrim); however, this agent was also susceptible to resistance, and fluoroquinolones became the new first-line choice.
