NSAIDs, Aspirin, and Breast Cancer Risk

A new study from the University of Southern California in Los Angeles indicates that women using the NSAID ibuprofen every day for five years or longer are 50% more likely than non-users to develop breast cancer, whereas women using aspirin every day for five years or longer are 81 percent more likely than non-users to develop the estrogen-receptor, or progesterone receptor-negative, subtype of cancer.

The researchers had expected NSAIDs to reduce the risk of cancer.

No link was observed between acetaminophen use and breast cancer risk.

Further study is needed, in view of the well-known benefits of low-dose aspirin for preventing cardiovascular disease.