Darifenacin for Overactive Bladder

Overactive Bladder

Results of two separate phase 3 studies involving darafenacin hydrobromide (Enablex®, Novartis), an M3 selective receptor antagonist being developed for the treatment of overactive bladder, reduced the frequency of weekly incontinence episodes (up to 77%) compared with placebo. It also decreased the number of weekly nocturnal awakenings caused by overactive bladder by 23%, versus 3.6% with placebo.
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